TRIB1 anticorps (AA 203-372)

N° du produit ABIN6149494

L’anticorps Lapin Polyclonal anti-TRIB1 a été validé pour WB. Il convient pour détecter TRIB1 dans des échantillons de Humain.

Aperçu rapide pour TRIB1 anticorps (AA 203-372) (ABIN6149494)

Antigène: TRIB1 (Tribbles Homolog 1 (TRIB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRIB1 anticorps

Épitope: AA 203-372

Séquence: LGDLKLRKFV FSTEERTQLR LESLEDTHIM KGEDDALSDK HGCPAYVSPE ILNTTGTYSG KAADVWSLGV MLYTLLVGRY PFHDSDPSAL FSKIRRGQFC IPEHISPKAR CLIRSLLRRE PSERLTAPEI LLHPWFESVL EPGYIDSEIG TSDQIVPEYQ EDSDISSFFC

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 203-372 of human TRIB1 (NP_079471.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TRIB1

Antigène: TRIB1 (Tribbles Homolog 1 (TRIB1))

Autre désignation: TRIB1

Sujet: Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase. The COP1-binding motif is masked by autoinhibitory interactions with the protein kinase domain. Serves to alter COP1 substrate specificity by directing the activity of COP1 toward CEBPA. Binds selectively the recognition sequence of CEBPA. Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner (By similarity. Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity. Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity.,TRIB1,C8FW,GIG-2,GIG2,SKIP1,TRB-1,TRB1,Signal Transduction,Kinase,Endocrine & Metabolism,Stem Cells,Hematopoietic Progenitors,Cardiovascular,TRIB1

Poids moléculaire: 23 kDa/41 kDa

ID gène: 10221

UniProt: Q96RU8

Pathways: Smooth Muscle Cell Migration