UMPS anticorps (AA 100-260)

N° du produit ABIN6149927

Cet anticorps Lapin Polyclonal détecte spécifiquement UMPS dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour UMPS anticorps (AA 100-260) (ABIN6149927)

Antigène: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UMPS est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-UMPS anticorps

Épitope: AA 100-260

Séquence: TKDYGTKRLV EGTINPGETC LIIEDVVTSG SSVLETVEVL QKEGLKVTDA IVLLDREQGG KDKLQAHGIR LHSVCTLSKM LEILEQQKKV DAETVGRVKR FIQENVFVAA NHNGSPLSIK EAPKELSFGA RAELPRIHPV ASKLLRLMQK KETNLCLSAD V

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human UMPS (NP_000364.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UMPS

Antigène: UMPS (Uridine Monophosphate Synthetase (UMPS))

Autre désignation: UMPS

Sujet: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.,UMPS,OPRT,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,UMPS

Poids moléculaire: 22 kDa/33 kDa/42 kDa/52 kDa

ID gène: 7372

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process