UMPS anticorps (AA 181-480)

N° du produit ABIN6149928

L’anticorps Lapin Polyclonal anti-UMPS a été validé pour WB. Il convient pour détecter UMPS dans des échantillons de Humain.

Aperçu rapide pour UMPS anticorps (AA 181-480) (ABIN6149928)

Antigène: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UMPS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UMPS anticorps

Épitope: AA 181-480

Séquence: EILEQQKKVD AETVGRVKRF IQENVFVAAN HNGSPLSIKE APKELSFGAR AELPRIHPVA SKLLRLMQKK ETNLCLSADV SLARELLQLA DALGPSICML KTHVDILNDF TLDVMKELIT LAKCHEFLIF EDRKFADIGN TVKKQYEGGI FKIASWADLV NAHVVPGSGV VKGLQEVGLP LHRGCLLIAE MSSTGSLATG DYTRAAVRMA EEHSEFVVGF ISGSRVSMKP EFLHLTPGVQ LEAGGDNLGQ QYNSPQEVIG KRGSDIIIVG RGIISAADRL EAAEMYRKAA WEAYLSRLGV

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 181-480 of human UMPS (NP_000364.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UMPS

Antigène: UMPS (Uridine Monophosphate Synthetase (UMPS))

Autre désignation: UMPS

Sujet: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.,UMPS,OPRT,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,UMPS

Poids moléculaire: 22 kDa/33 kDa/42 kDa/52 kDa

ID gène: 7372

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process