ZEB1 anticorps (AA 1-260)

N° du produit ABIN6150422

Cet anticorps Lapin Polyclonal détecte spécifiquement ZEB1 dans WB et IHC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour ZEB1 anticorps (AA 1-260) (ABIN6150422)

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZEB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ZEB1 anticorps

Épitope: AA 1-260

Séquence: MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESVTDA ADCEGVPEDD LPTDQTVLPG RSSEREGNAK NCWEDDTGKE GQEILGPEAQ ADEAGCTVKD DECESDAENE QNHDPNVEEF LQQQDTAVIF PEAPEEDQRQ GTPEASGHDE NGTPDAFSQL LTCPYCDRGY KRFTSLKEHI KYRHEKNEDN FSCSLCSYTF AYRTQLERHM TSHKSGRDQR HVTQSGCNRK FKCTECGKAF KYKHHLKEHL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ZEB1 (NP_001167567.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-ZEB1 (ABIN6150422)

Ju, Chen, Deng, Liu, Wang, Wang, Nie, Wang, Ding, Yao, Gui, Li, Xu, Ma, Song, Kvansakul, Zen, Zhang, Luo, Fang, Huang, Allis, Tan, Zeng, Wei, Zhao: "NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression." dans: Nature communications, Vol. 8, Issue 1, pp. 928, (2018) (PubMed).

Liang, Yang, Guan, Lv, Qu, Fu, Zhao: "LncRNA UCA1 sponges miR-204-5p to promote migration, invasion and epithelial-mesenchymal transition of glioma cells via upregulation of ZEB1." dans: Pathology, research and practice, Vol. 214, Issue 9, pp. 1474-1481, (2018) (PubMed).

Détails sur ZEB1

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Autre désignation: ZEB1

Sujet: This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.,ZEB1,AREB6,BZP,DELTAEF1,FECD6,NIL2A,PPCD3,TCF8,ZFHEP,ZFHX1A,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Wnt/β-Catenin Signaling Pathway,ZEB1

Poids moléculaire: 116 kDa/122 kDa/124 kDa

ID gène: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation