S100A8/A9 Complex (Calprotectin) anticorps (CF®640R)

N° du produit ABIN6152279

Cet anticorps anti-S100A8/A9 Complex (Calprotectin) est un anticorps Souris Monoclonal détectant S100A8/A9 Complex (Calprotectin) dans FACS, IF et IHC (f). Adapté pour Humain, Porc, Boeuf (Vache), Cat, Chien, Cobaye, Singe, Lapin, Rat, Souris, Cheval, Babouin et Chévre.

Aperçu rapide pour S100A8/A9 Complex (Calprotectin) anticorps (CF®640R) (ABIN6152279)

Antigène: S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))

Reactivité: Humain, Porc, Boeuf (Vache), Cat, Chien, Cobaye, Singe, Lapin, Rat, Souris, Cheval, Babouin, Chévre

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A8/A9 Complex (Calprotectin) est conjugé à/à la CF®640R

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: MAC387

Détail du produit anti-S100A8/A9 Complex (Calprotectin) anticorps (CF®640R)

Fonction: Mouse Monoclonal anti-Calgranulin-B / MRP-8/-14 / MAC-387 / S100A8/A9 / Macrophage Ag (MAC387), CF640R Conjugate

Attributs du produit: This antibody recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Affinity purified monocyte membrane preparation

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunohistology formalin-fixed 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Tonsil, lymph node, or spleen

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur S100A8/A9 Complex (Calprotectin)

Antigène: S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))

Autre désignation: Calgranulin-B / MRP-8/-14 / MAC-387 / S100A8/A9 / Macrophage Ag

Poids moléculaire: 12-14 kDa (doublet)

ID gène: 6279, 6280

Pathways: S100 Proteins