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dsDNA anticorps (CF®640R)

Cet anticorps anti-dsDNA est un anticorps Souris Monoclonal détectant dsDNA dans FACS et IF. Adapté pour Humain.
N° du produit ABIN6152393

Aperçu rapide pour dsDNA anticorps (CF®640R) (ABIN6152393)

Antigène

dsDNA (Double-Stranded DNA (dsDNA))

Reactivité

  • 15
  • 2
  • 1
Humain

Hôte

  • 18
  • 2
Souris

Clonalité

  • 18
  • 2
Monoclonal

Conjugué

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp dsDNA est conjugé à/à la CF®640R

Application

  • 13
  • 12
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

Clone

121-3
  • Fonction

    Mouse Monoclonal anti-Double-Stranded DNA (dsDNA) (121-3), CF640R Conjugate

    Attributs du produit

    This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Deoxyribonucleic acid (DNA) is a long polymer of nucleotides that is held together by a backbone made of sugars and phosphate groups. It holds the genetic instructions for the development and function of living things. DNA is crucial for living organisms, and all known cellular life and some viruses contain DNA. In eukaryotes, DNA exists in the cell nucleus, while in prokaryotes, DNA is located in the cytoplasm. In living organisms, DNA does not usually exist as a single molecule, but instead as a tightly associated pair of molecules in the shape of a right-handed double helix. Hydrogen bonds as well as forces generated by the hydrophobic effect and pi stacking hold the two DNA strands together. During replication and transcription, portions of the helix unwind and become single stranded. Protective proteins surround these single-stranded DNA. Double stranded (ds) DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Nuclei of Burkitt',s cells

    Isotype

    IgG3 kappa
  • Indications d'application

    Flow Cytometry 0.5-1 μg/million cells/0.1 mLImmunofluorescence 1-2 μg/mL

    Commentaires

    Tonsil

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    100 μg/mL

    Buffer

    PBS/0.1 % BSA/0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light
  • Antigène

    dsDNA (Double-Stranded DNA (dsDNA))

    Classe de substances

    Nucleotide
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