TLR7 anticorps (AA 900-950)

N° du produit ABIN615823

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR7 dans WB et IHC (p). Il présente une réactivité envers Humain, Souris, Rat, Singe, Chien, Boeuf (Vache) et Cheval.

Aperçu rapide pour TLR7 anticorps (AA 900-950) (ABIN615823)

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivité: Humain, Souris, Rat, Singe, Chien, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TLR7 anticorps

Épitope: AA 900-950

Specificité: This antibody reacts to Toll-like Receptor 7 (TLR7).

Purification: Protein G Chromatography

Immunogène: Synthetic peptide - KLH conjugated, A portion of amino acids 900-950 of human TLR7 Genename: TLR7

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: PBS containing 0.2 % gelatin and 0.05 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TLR7

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Autre désignation: TLR7

Sujet: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNa secretion, suggesting the importance of TLR7 in virus recognition.Synonyms: Toll-like receptor 7

ID gène: 51284

NCBI Accession: NP_057646

UniProt: Q9NYK1

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades