XIAP anticorps (AA 75-226)

N° du produit ABIN615851

L’anticorps anti-XIAP Polyclonal Lapin est utilisé pour la détection de XIAP dans des échantillons de Humain. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour XIAP anticorps (AA 75-226) (ABIN615851)

Antigène: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XIAP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-XIAP anticorps

Épitope: AA 75-226

Specificité: This antibody reacts to X-linked Inhibitor Of Apoptosis Protein XIAP (XIAP/BIRC4).

Réactivité croisée (Details): Species reactivity (expected):Mouse (88 %), Rat (90 %), Rabbit (94 %), Pig (92 %).
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 75 and 226 of BIRC4. Genename: XIAP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.1 M Tris-Glycine, pH 7.0 containing 10 % Glycerol and 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur XIAP

Antigène: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Autre désignation: IAP3 / BIRC4

Sujet: Apoptosis inhibitor 3 (API3) is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, API3 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. API3 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.Synonyms: API3, Baculoviral IAP repeat-containing protein 4, E3 ubiquitin-protein ligase XIAP, HILP, Inhibitor of apoptosis protein 3, X-linked IAP, X-linked inhibitor of apoptosis protein, XIAP

ID gène: 331

NCBI Accession: NP_001158

UniProt: P98170

Pathways: Apoptose, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis