DUOX1 anticorps (Internal Region)

N° du produit ABIN615993

Cet anticorps anti-DUOX1 est un anticorps Chèvre Polyclonal détectant DUOX1 dans IHC (p) et EIA. Adapté pour Humain.

Aperçu rapide pour DUOX1 anticorps (Internal Region) (ABIN615993)

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DUOX1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-DUOX1 anticorps

Épitope: Internal Region

Séquence: EKFQRSCLHQ TVQ

Specificité: This antibody is expected to recognise both reported isoforms (NP_059130.2, NP_787954.1) which are identical.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_059130.2 , NP_787954.1. Genename: DUOX1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DUOX1

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Autre désignation: Dual Oxidase 1

Sujet: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene (from EntrezGene).Synonyms: DUOX, DUOX1, LNOX1, Large NOX 1, Long NOX 1, NADPH thyroid oxidase 1, THOX1, Thyroid oxidase 1

ID gène: 53905

NCBI Accession: NP_059130

UniProt: Q9NRD9