CD16 anticorps (CF®640R)

N° du produit ABIN6173619

Cet anticorps anti-CD16 est un anticorps Souris Monoclonal détectant CD16 dans FACS, IF et Func. Adapté pour Humain.

Aperçu rapide pour CD16 anticorps (CF®640R) (ABIN6173619)

Antigène: CD16

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD16 est conjugé à/à la CF®640R

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: HuNK2

Détail du produit anti-CD16 anticorps (CF®640R)

Fonction: Mouse Monoclonal anti-CD16 (HuNK2), CF640R Conjugate

Attributs du produit: This antibody recognizes a protein of 50-65 kDa, identified as CD16 (Workshop IV, Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Human peripheral blood lymphocytes from a NK-leukemia patient.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Functional Studies order Ab without BSA & azide)
• Optimal dilution for a specific application should be determined by user

Commentaires:

K-562 or U-937 cells. Lymph nodes and tonsils.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur CD16

Antigène: CD16

Autre désignation: CD16

Poids moléculaire: 50-80 kDa

ID gène: 2214, 372679

UniProt: P08637

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process