CD55 anticorps (Biotin)
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- Antigène Voir toutes CD55 Anticorps
- CD55 (Complement Decay-Accelerating Factor (CD55))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD55 est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Fonction
- Mouse Monoclonal anti-CD55 (DAF) (143-30), Biotin Conjugate
- Attributs du produit
- This antibody recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- PHA stimulated human PBL
- Clone
- 143-30
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD55 Anticorps primaire
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- Indications d'application
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Immunohistology (frozen) 0.5-1 μg/mL
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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Jurkat, HUT-78, K562, YT, U937, MG63, and human lymphocytes. Human lymph nodes and tonsils.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Antigène
- CD55 (Complement Decay-Accelerating Factor (CD55))
- Autre désignation
- CD55 (DAF) (CD55 Produits)
- Synonymes
- anticorps CR, anticorps CROM, anticorps DAF, anticorps TC, anticorps Daf, anticorps Daf-GPI, anticorps Daf1, anticorps GPI-DAF, anticorps CD55 molecule (Cromer blood group), anticorps CD55 molecule, decay accelerating factor for complement, anticorps CD55, anticorps Cd55
- Poids moléculaire
- 70 kDa
- ID gène
- 1604, 126517
- UniProt
- P08174
- Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity
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