GJB1 anticorps (CF®405S)
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- Antigène Voir toutes GJB1 Anticorps
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GJB1 est conjugé à/à la CF®405S
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Fonction
- Mouse Monoclonal anti-Connexin-32 (GJB1/1753), CF405S Conjugate
- Attributs du produit
- This Ab recognizes a protein of 27-32 kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane ?-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities, therefore, one connexin usually cannot fully substitute for another. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant human GJB1 protein
- Clone
- GJB1-1753
- Isotype
- IgG
- Top Product
- Discover our top product GJB1 Anticorps primaire
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- Indications d'application
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Immunohistology (formalin) 1-2 μg/mL
- Immunofluorescence 1-2 μg/mL Flow cytometry 0.5-1 μg/million cells
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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MCF-7 Cells. Liver, Kidney, Stomach or Tonsil
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
- Autre désignation
- Connexin-32 (GJB1 Produits)
- Synonymes
- anticorps GJIC, anticorps cmtx, anticorps cmtx1, anticorps connexin-30, anticorps connexin32, anticorps cx30, anticorps cx32, anticorps gja1, anticorps CX32, anticorps GJB1, anticorps AI118175, anticorps Cnx32, anticorps Cx32, anticorps Gjb-1, anticorps CMTX, anticorps CMTX1, anticorps gjb1-a, anticorps gap junction protein beta 1, anticorps connexin 32, anticorps probable serine/threonine-protein kinase CST, anticorps gap junction protein, beta 1, anticorps gap junction protein beta 1 L homeolog, anticorps gjb1, anticorps CX32, anticorps LOC9303136, anticorps GJB1, anticorps Gjb1, anticorps gjb1.L
- Sujet
- Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28 kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1
- Poids moléculaire
- 27-32 kDa
- ID gène
- 2705, 333303
- UniProt
- P08034
- Pathways
- Cell-Cell Junction Organization
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