GRIA4 anticorps (Internal Region)

N° du produit ABIN618029

L’anticorps Chèvre Polyclonal anti-GRIA4 a été validé pour WB, ELISA et IHC. Il convient pour détecter GRIA4 dans des échantillons de Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour GRIA4 anticorps (Internal Region) (ABIN618029)

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GRIA4 anticorps

Épitope: Internal Region

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat (Rattus)

Purification: affinity purified

Immunogène: Synthetic peptide: C-KKLDQREYPGSETP, from the internal region of the protein sequence according to NP_000820.3, NP_001070711.1, NP_001070712.1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur GRIA4

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Autre désignation: GLUR4C

Sujet: Human glutamate receptor 4 (GRIA4) is a new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. Binding studies showed that human GluR4 transfected into simian kidney cells (COS-1) exhibits high specific binding for[3H](RS)-alpha-amino- 3-hydroxy-5-methylisoxazole-4-propionic acid ([3H]AMPA) but not [3H]kainate. Ion substitution experiments indicate that hGluR4 receptor-linked ion channels in their homomeric state are permeable to both CA2+ and Na+ ions. Immunoprecipitation studies suggest that GRIA1 exists in situ in the form of a pentamer.

NCBI Accession: NP_000820, NP_001070712, NP_001070711

Pathways: Signalisation PI3K-Akt