CD70 anticorps (CF®568)

N° du produit ABIN6185104

L’anticorps Souris Monoclonal anti-CD70 a été validé pour ELISA, FACS, IP, IF, IHC (fro), Coat et ProA. Il convient pour détecter CD70 dans des échantillons de Humain.

Aperçu rapide pour CD70 anticorps (CF®568) (ABIN6185104)

Antigène: CD70 (CD70 Molecule (CD70))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD70 est conjugé à/à la CF®568

Application: ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Coating (Coat), Proliferation Assay (ProA)

Clone: BU69

Détail du produit anti-CD70 anticorps (CF®568)

Fonction: Mouse Monoclonal anti-CD70 (BU69), CF568 Conjugate

Attributs du produit: This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toinhibit T cell proliferation induced by dendritic cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Human WM-1 (Waldenstrom s macroglobulinemia) cell line

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunohistology (frozen) 0.5-1 μg/mL

• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunoprecipitation 0.5-1 μg/500 μg protein lysate
• ELISA For coating, order Ab without BSA
• Inhibits T cell proliferation induced by dendritic cells
• Optimal dilution for a specific application should be determined by user

Commentaires:

Raji cells. Lymph node or tonsil.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70

Sujet: CD27 ligand (CD27L), CD27LG, Ki24, Surface antigen CD70, Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7)

Poids moléculaire: ~30 kDa

ID gène: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints