Transferrin Receptor anticorps (CF®405S)

N° du produit ABIN6185204

Cet anticorps anti-Transferrin Receptor est un anticorps Souris Monoclonal détectant Transferrin Receptor dans FACS, WB et IF. Adapté pour Humain.

Aperçu rapide pour Transferrin Receptor anticorps (CF®405S) (ABIN6185204)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est conjugé à/à la CF®405S

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

Clone: DF1513

Détail du produit anti-Transferrin Receptor anticorps (CF®405S)

Fonction: Mouse Monoclonal anti-CD71 (DF1513), CF405S Conjugate

Attributs du produit: This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: KG1 acute myeloid leukemia cell line

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1.0 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: CD71

Sujet: Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

Poids moléculaire: 85-95 kDa (monomer), 190 kDa (dimer)

ID gène: 7037, 529618

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis