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Prostate Specific Antigen anticorps (CF®405S)

Cet anticorps anti-Prostate Specific Antigen est un anticorps Souris Monoclonal détectant Prostate Specific Antigen dans IF, FACS et IHC (f). Adapté pour Humain.
N° du produit ABIN6190372

Aperçu rapide pour Prostate Specific Antigen anticorps (CF®405S) (ABIN6190372)

Antigène

Voir toutes Prostate Specific Antigen (PSA) Anticorps
Prostate Specific Antigen (PSA)

Reactivité

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Humain

Hôte

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Souris

Clonalité

  • 128
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Monoclonal

Conjugué

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Cet anticorp Prostate Specific Antigen est conjugé à/à la CF®405S

Application

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone

A67-B-E3
  • Fonction

    Mouse Monoclonal anti-PSA (Prostate Specific Antigen) (A67-B/E3), CF405S Conjugate

    Attributs du produit

    This antibody recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb 1A7G6B6 for PSA tests. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    PSA (p30) from human sperm plasma

    Isotype

    IgG1 kappa
  • Indications d'application

    Immunohistology formalin-fixed 0.25-0.5 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    Commentaires

    PC12 cells or normal prostate or prostate carcinoma

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    100 μg/mL

    Buffer

    PBS/0.1 % BSA/0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light
  • Antigène

    Prostate Specific Antigen (PSA)

    Autre désignation

    PSA (Prostate Specific Antigen)

    Sujet

    Antigen, prostate-specific (APS), Gamma-seminoprotein, hK3, Kallikrein related peptidase 3, Kallikrein-3 (KLK3), KLK2A1, P-30 antigen, Semenogelase, Seminin

    Poids moléculaire

    33-34 kDa

    ID gène

    354, 171995

    UniProt

    P07288

    Pathways

    Système du Complément
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