Ret Proto-Oncogene anticorps (AA 29-300)

N° du produit ABIN6146873

L’anticorps Lapin Polyclonal anti-Ret Proto-Oncogene a été validé pour WB, IHC et IF. Il convient pour détecter Ret Proto-Oncogene dans des échantillons de Humain.

Aperçu rapide pour Ret Proto-Oncogene anticorps (AA 29-300) (ABIN6146873)

Antigène: Ret Proto-Oncogene (RET)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ret Proto-Oncogene est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Ret Proto-Oncogene anticorps

Épitope: AA 29-300

Séquence: LYFSRDAYWE KLYVDQAAGT PLLYVHALRD APEEVPSFRL GQHLYGTYRT RLHENNWICI QEDTGLLYLN RSLDHSSWEK LSVRNRGFPL LTVYLKVFLS PTSLREGECQ WPGCARVYFS FFNTSFPACS SLKPRELCFP ETRPSFRIRE NRPPGTFHQF RLLPVQFLCP NISVAYRLLE GEGLPFRCAP DSLEVSTRWA LDREQREKYE LVAVCTVHAG AREEVVMVPF PVTVYDEDDS APTFPAGVDT ASAVVEFKRK EDTVVATLRV FD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 29-300 of human Ret (NP_066124.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Ret Proto-Oncogene

Antigène: Ret Proto-Oncogene (RET)

Autre désignation: RET

Sujet: This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.,RET,CDHF12,CDHR16,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET-ELE1,RET51,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,RET

Poids moléculaire: 119 kDa/124 kDa

ID gène: 5979

UniProt: P07949

Pathways: Signalisation RTK, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation