Fibrillarin anticorps

N° du produit ABIN3021515

Cet anticorps anti-Fibrillarin est un anticorps Lapin Polyclonal détectant Fibrillarin dans WB et IHC. Adapté pour Humain, Rat et Souris. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Fibrillarin anticorps (ABIN3021515)

Antigène: Fibrillarin (FBL)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrillarin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Fibrillarin anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human FBL

Isotype: IgG

Information d'application

Indications d'application: Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C/-80 °C

Références pour anticorps anti-Fibrillarin (ABIN3021515)

Zheng, Xiong, Wu, Chen, Chen, Fleming, Gao, Bi, Ge: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." dans: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).

Détails sur Fibrillarin

Antigène: Fibrillarin (FBL)

Autre désignation: FBL

Sujet: Fibrillarin is a 2-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.
Synonyms: FBL, FIB, FLRN, RNU3IP1

ID gène: 2091

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process