CBX3 anticorps

N° du produit ABIN6241538

Cet anticorps Souris Monoclonal détecte spécifiquement CBX3 dans WB, IHC, IP et ICC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CBX3 anticorps (ABIN6241538)

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBX3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Détail du produit anti-CBX3 anticorps

Immunogène: Recombinant Protein

Information d'application

Indications d'application: IP: 1:500. WB: 1:1000. IHC: 1:100. ICC: 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C,-20 °C

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: HP1-gamma

Sujet: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.

UniProt: Q13185