This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This FKBP1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the Central region of human FKBP1A.
FKBP1A
Reactivité: Humain
WB
Hôte: Lapin
Monoclonal
unconjugated
Indications d'application
WB: 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Antigène
FKBP1A
(FK506 Binding Protein 1A, 12kDa (FKBP1A))
Autre désignation
FKBP1A
Sujet
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.