IL-11 anticorps (AA 27-61)
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- Antigène Voir toutes IL-11 (IL11) Anticorps
- IL-11 (IL11) (Interleukin 11 (IL11))
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Épitope
- AA 27-61
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-11 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This IL11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-61 amino acids from human IL11.
- Clone
- RB56890
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IL11 Anticorps primaire
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- Indications d'application
- WB: 1:2000. FC: 1:25
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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- Antigène
- IL-11 (IL11) (Interleukin 11 (IL11))
- Autre désignation
- IL11 (IL11 Produits)
- Synonymes
- anticorps IL11, anticorps AGIF, anticorps IL-11, anticorps Il-11, anticorps interleukin 11, anticorps IL11, anticorps Il11
- Sujet
- Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:< a href="http://www.uniprot.org/citations/2145578" target="_blank">2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:< a href="http://www.uniprot.org/citations/12919066" target="_blank">12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
- Poids moléculaire
- 21429
- UniProt
- P20809
- Pathways
- Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
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