IL-11 anticorps (AA 27-61)

N° du produit ABIN6242412

L’anticorps anti-IL-11 Polyclonal Lapin est utilisé pour la détection de IL-11 dans des échantillons de Humain. Il a été validé pour WB et FACS.

Aperçu rapide pour IL-11 anticorps (AA 27-61) (ABIN6242412)

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-11 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB56890

Détail du produit anti-IL-11 anticorps

Épitope: AA 27-61

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IL11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-61 amino acids from human IL11.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur IL-11

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Autre désignation: IL11

Sujet: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:< a href="http://www.uniprot.org/citations/2145578" target="_blank">2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:< a href="http://www.uniprot.org/citations/12919066" target="_blank">12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

Poids moléculaire: 21429

UniProt: P20809

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion