MBD2 anticorps (AA 10-228)

N° du produit ABIN6242434

Cet anticorps anti-MBD2 Monoclonal Souris (Clone 1812CT625-9-45) (ABIN6242434) détecte spécifiquement MBD2 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MBD2 anticorps (AA 10-228) (ABIN6242434)

Antigène: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MBD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1812CT625-9-45

Détail du produit anti-MBD2 anticorps

Épitope: AA 10-228

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur MBD2

Antigène: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Autre désignation: MBD2

Sujet: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.

Poids moléculaire: 43255

UniProt: Q9UBB5

Pathways: Chromatin Binding