TNIK anticorps (Ser764)

N° du produit ABIN6242564

Détail du produit anti-TNIK anticorps

Antigène: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Épitope: Ser764

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNIK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TNIK(S764) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human TNIK(S764).

Clone: RB59089

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500. WB: 1:500. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur TNIK

Antigène: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Autre désignation: TNIK (TNIK Produits)

Synonymes: anticorps RGD1561817, anticorps TNIK, anticorps 1500031A17Rik, anticorps 4831440I19Rik, anticorps AI451411, anticorps C530008O15Rik, anticorps C630040K21Rik, anticorps fc52d11, anticorps msn, anticorps tnikl, anticorps wu:fc52d11, anticorps zgc:63535, anticorps im:6898857, anticorps zgc:123033, anticorps zgc:152783, anticorps tnik, anticorps TRAF2 and NCK interacting kinase, anticorps TRAF2 and NCK interacting kinase a, anticorps TRAF2 and NCK interacting kinase b, anticorps TRAF2 and NCK interacting kinase S homeolog, anticorps TNIK, anticorps Tnik, anticorps tnika, anticorps tnikb, anticorps tnik.S

Sujet: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.

Poids moléculaire: 154943

UniProt: Q9UKE5