TNIK anticorps (AA 523-714)

N° du produit ABIN7172340

Détail du produit anti-TNIK anticorps

Antigène: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Épitope: AA 523-714

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNIK est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human TRAF2 and NCK-interacting protein kinase protein (523-714AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TNIK

Antigène: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Autre désignation: TNIK (TNIK Produits)

Synonymes: anticorps RGD1561817, anticorps TNIK, anticorps 1500031A17Rik, anticorps 4831440I19Rik, anticorps AI451411, anticorps C530008O15Rik, anticorps C630040K21Rik, anticorps fc52d11, anticorps msn, anticorps tnikl, anticorps wu:fc52d11, anticorps zgc:63535, anticorps im:6898857, anticorps zgc:123033, anticorps zgc:152783, anticorps tnik, anticorps TRAF2 and NCK interacting kinase, anticorps TRAF2 and NCK interacting kinase a, anticorps TRAF2 and NCK interacting kinase b, anticorps TRAF2 and NCK interacting kinase S homeolog, anticorps TNIK, anticorps Tnik, anticorps tnika, anticorps tnikb, anticorps tnik.S

Sujet:

Background: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.

Aliases: EC 2.7.11.1 antibody, KIAA0551 antibody, Tnik antibody, TNIK_HUMAN antibody, Traf2 and NCK interacting kinase antibody, Traf2 and NCK-interacting protein kinase antibody

UniProt: Q9UKE5