Prohibitin 2 anticorps (C-Term)

N° du produit ABIN6242574

L’anticorps Lapin Polyclonal anti-Prohibitin 2 a été validé pour WB et IHC (p). Il convient pour détecter Prohibitin 2 dans des échantillons de Humain.

Aperçu rapide pour Prohibitin 2 anticorps (C-Term) (ABIN6242574)

Antigène: Prohibitin 2 (PHB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB10631

Détail du produit anti-Prohibitin 2 anticorps

Épitope: AA 197-226, C-Term

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This REA (PHB2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the C-terminal region of human REA (PHB2).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur Prohibitin 2

Antigène: Prohibitin 2 (PHB2)

Autre désignation: REA

Sujet: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

Poids moléculaire: 33296

NCBI Accession: NP_001138303, NP_001254629

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling