RNF7 anticorps (N-Term)

N° du produit ABIN6242612

Détail du produit anti-RNF7 anticorps

Antigène: RNF7 (Ring Finger Protein 7 (RNF7))

Épitope: AA 25-57, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RNF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-57 amino acids from the N-terminal region of human RNF7.

Clone: RB52911

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:8000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur RNF7

Antigène: RNF7 (Ring Finger Protein 7 (RNF7))

Autre désignation: RNF7 (RNF7 Produits)

Synonymes: anticorps CKBBP1, anticorps ROC2, anticorps SAG, anticorps Rbx2, anticorps ring finger protein 7, anticorps RNF7, anticorps Rnf7

Sujet: Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.

Poids moléculaire: 12683

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity