RNF7 anticorps

N° du produit ABIN7263303

Détail du produit anti-RNF7 anticorps

Antigène: RNF7 (Ring Finger Protein 7 (RNF7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF7 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human RNF7 (NP_055060.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:20-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RNF7

Antigène: RNF7 (Ring Finger Protein 7 (RNF7))

Autre désignation: RNF7 (RNF7 Produits)

Synonymes: anticorps CKBBP1, anticorps ROC2, anticorps SAG, anticorps Rbx2, anticorps ring finger protein 7, anticorps RNF7, anticorps Rnf7

Sujet: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

ID gène: 9616

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity