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SRY anticorps (AA 81-112)

Cet anticorps Lapin Polyclonal détecte spécifiquement SRY dans WB. Il présente une réactivité envers Humain.
N° du produit ABIN6242645

Aperçu rapide pour SRY anticorps (AA 81-112) (ABIN6242645)

Antigène

Voir toutes SRY Anticorps
SRY (Sex Determining Region Y (SRY))

Reactivité

  • 28
  • 13
  • 2
  • 1
  • 1
Humain

Hôte

  • 33
  • 10
Lapin

Clonalité

  • 35
  • 8
Polyclonal

Conjugué

  • 27
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SRY est non-conjugé

Application

  • 27
  • 21
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Clone

RB53826
  • Épitope

    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-112

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This SRY antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 81-112 amino acids from the Central region of human SRY.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Date de péremption

    6 months
  • Antigène

    SRY (Sex Determining Region Y (SRY))

    Autre désignation

    SRY

    Sujet

    Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.

    Poids moléculaire

    23884

    UniProt

    Q05066
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