UNC5B anticorps (AA 507-541)

N° du produit ABIN6242756

Cet anticorps Lapin Polyclonal détecte spécifiquement UNC5B dans WB. Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour UNC5B anticorps (AA 507-541) (ABIN6242756)

Antigène: UNC5B (Netrin receptor UNC5B (UNC5B))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC5B est non-conjugé

Application: Western Blotting (WB)

Clone: RB52980

Détail du produit anti-UNC5B anticorps

Épitope: AA 507-541

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UNC5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 507-541 amino acids from the Central region of human UNC5B.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur UNC5B

Antigène: UNC5B (Netrin receptor UNC5B (UNC5B))

Autre désignation: UNC5B

Sujet: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity.

Poids moléculaire: 103638

UniProt: Q8IZJ1