UNC5B anticorps (AA 507-541)

N° du produit ABIN6242756

Détail du produit anti-UNC5B anticorps

Antigène: UNC5B (Netrin receptor UNC5B (UNC5B))

Épitope: AA 507-541

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC5B est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UNC5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 507-541 amino acids from the Central region of human UNC5B.

Clone: RB52980

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur UNC5B

Antigène: UNC5B (Netrin receptor UNC5B (UNC5B))

Autre désignation: UNC5B (UNC5B Produits)

Synonymes: anticorps unc5h2, anticorps 6330415E02Rik, anticorps A630020F16, anticorps D10Bwg0792e, anticorps Unc5h2, anticorps UNC5H2, anticorps p53RDL1, anticorps UNC5C, anticorps UNC5B, anticorps p53rdl1, anticorps unc-5 netrin receptor B, anticorps unc-5 netrin receptor B L homeolog, anticorps unc5b, anticorps Unc5b, anticorps UNC5B, anticorps unc5b.L

Sujet: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity.

Poids moléculaire: 103638

UniProt: Q8IZJ1