DDX42 anticorps (AA 104-138)
Aperçu rapide pour DDX42 anticorps (AA 104-138) (ABIN6242791)
Antigène
Voir toutes DDX42 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 104-138
-
Homologie
- M
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogène
- This DDX42 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 104-138 amino acids from human DDX42.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- WB: 1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Date de péremption
- 6 months
-
-
- DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))
-
Autre désignation
- DDX42
-
Sujet
- ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
-
Poids moléculaire
- 102975
-
UniProt
- Q86XP3
Antigène
-