DDX42 anticorps (AA 104-138)

N° du produit ABIN6242791

Détail du produit anti-DDX42 anticorps

Antigène: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Épitope: AA 104-138

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX42 est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DDX42 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 104-138 amino acids from human DDX42.

Clone: RB54203

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur DDX42

Antigène: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Autre désignation: DDX42 (DDX42 Produits)

Synonymes: anticorps im:7148194, anticorps si:dkey-15n1.10, anticorps zgc:111815, anticorps DDX42P, anticorps RHELP, anticorps RNAHP, anticorps SF3b125, anticorps 1810047H21Rik, anticorps AW319508, anticorps AW556242, anticorps B430002H05Rik, anticorps DEAD (Asp-Glu-Ala-Asp) box helicase 42, anticorps DEAD-box helicase 42, anticorps DEAD-box helicase 42 L homeolog, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 42, anticorps ddx42, anticorps DDX42, anticorps Ddx42, anticorps ddx42.L

Sujet: ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

Poids moléculaire: 102975

UniProt: Q86XP3