DDX42 anticorps (C-Term)

N° du produit ABIN6261256

Détail du produit anti-DDX42 anticorps

Antigène: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX42 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificité: DDX42 Antibody detects endogenous levels of total DDX42.

Homologie: Pig,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DDX42, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DDX42

Antigène: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Autre désignation: DDX42 (DDX42 Produits)

Synonymes: anticorps im:7148194, anticorps si:dkey-15n1.10, anticorps zgc:111815, anticorps DDX42P, anticorps RHELP, anticorps RNAHP, anticorps SF3b125, anticorps 1810047H21Rik, anticorps AW319508, anticorps AW556242, anticorps B430002H05Rik, anticorps DEAD (Asp-Glu-Ala-Asp) box helicase 42, anticorps DEAD-box helicase 42, anticorps DEAD-box helicase 42 L homeolog, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 42, anticorps ddx42, anticorps DDX42, anticorps Ddx42, anticorps ddx42.L

Sujet:

Description: ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

Gene: DDX42

Poids moléculaire: 103 kDa

ID gène: 11325

UniProt: Q86XP3