HES1 anticorps (AA 102-137)

N° du produit ABIN6242801

Cet anticorps Lapin Polyclonal détecte spécifiquement HES1 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour HES1 anticorps (AA 102-137) (ABIN6242801)

Antigène: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HES1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB50935

Détail du produit anti-HES1 anticorps

Épitope: AA 102-137

Homologie: X, B, H, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of Mouse Hes1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur HES1

Antigène: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Autre désignation: Hes1

Sujet: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).

Poids moléculaire: 29749

UniProt: P35428

Pathways: Réparation de l'ADN