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MLL3 anticorps (C-Term)

KMT2C Reactivité: Humain IHC (p) Hôte: Lapin Polyclonal RB52486 unconjugated
N° du produit ABIN6242808
  • Antigène Tous les produits MLL3 (KMT2C)
    MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))
    Épitope
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3784-3818, C-Term
    Reactivité
    Humain
    Hôte
    • 9
    • 1
    Lapin
    Clonalité
    • 9
    • 1
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MLL3 est non-conjugé
    Application
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3784-3818 amino acids from the C-terminal region of human MLL3.
    Clone
    RB52486
    Isotype
    Ig Fraction
  • Indications d'application
    IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))
    Autre désignation
    MLL3 (KMT2C Produits)
    Synonymes
    anticorps HALR, anticorps MLL3, anticorps E330008K23Rik, anticorps Mll3, anticorps mKIAA1506, anticorps lysine methyltransferase 2C, anticorps lysine (K)-specific methyltransferase 2C, anticorps KMT2C, anticorps Kmt2c
    Sujet
    Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
    Poids moléculaire
    541370
    UniProt
    Q8NEZ4
    Pathways
    L'effet Warburg
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