GNMT anticorps (C-Term)

N° du produit ABIN6242958

L’anticorps Lapin Polyclonal anti-GNMT a été validé pour WB. Il convient pour détecter GNMT dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour GNMT anticorps (C-Term) (ABIN6242958)

Antigène: GNMT (Glycine N-Methyltransferase (GNMT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNMT est non-conjugé

Application: Western Blotting (WB)

Clone: RB5760

Détail du produit anti-GNMT anticorps

Épitope: AA 218-248, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the C-terminal region of human GNMT.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-GNMT (ABIN6242958)

Wagner, Choi, Panzitt, Mamrosh, Lee, Zaufel, Xiao, Wooton-Kee, Ståhlman, Newgard, Borén, Moore: "Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism." dans: Hepatology (Baltimore, Md.), Vol. 63, Issue 1, pp. 95-106, (2016) (PubMed).

DiBello, Dayal, Kaveti, Zhang, Kinter, Lentz, Jacobsen: "The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia." dans: Molecular & cellular proteomics : MCP, Vol. 9, Issue 3, pp. 471-85, (2010) (PubMed).

Détails sur GNMT

Antigène: GNMT (Glycine N-Methyltransferase (GNMT))

Autre désignation: GNMT

Sujet: Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.

Poids moléculaire: 32742

NCBI Accession: NP_061833

UniProt: Q14749

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process