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MME anticorps (AA 472-505)

Name: MME anticorps (AA 472-505)
SKU: ABIN6243087
Price: 475.5 EUR
Availability: InStock

MME Reactivité: Humain FACS, WB, IHC (p) Hôte: Souris Monoclonal 965CT9-1-1 unconjugated

All lanes : Anti-E Antibody (Center) at 1:4000 dilution Lane 1: Human placenta lysate Lane 2: Ramos whole cell lysate Lane 3: Human kidney lysate Lysates/proteins at 20 μg per lane. (MME anticorps (AA 472-505))

Immunohistochemical analysis of paraffin-embedded human kidney tissue using (ABIN6243087 and ABIN6577253) performed on the Leica® BOND RXm. (MME anticorps (AA 472-505))

IHC (p)

Immunohistochemical analysis of paraffin-embedded Human kidney section using Pink1 (ABIN6243087 and ABIN6577253). (MME anticorps (AA 472-505))

IHC

Overlay histogram showing Jurkat cells stained with (ABIN6243087 and ABIN6577253)(green line). (MME anticorps (AA 472-505))

FACS

4 images

N° du produit ABIN6243087

Fiche de données

Antigène Voir toutes MME Anticorps

MME (Membrane Metallo-Endopeptidase (MME))
Épitope
16

14

10

8

8

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 472-505
Reactivité
213

58

50

3

2

2

2

2

2

1

1

1

1
Humain
Hôte
111

108

2
Souris
Anticorps secondaires appropriés
Clonalité
115

105

2
Monoclonal
Conjugué
108

19

19

14

9

6

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MME est non-conjugé
Application
132

100

80

69

38

29

21

21

13

13

10

8

6

5

5

3

2

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène

This MME antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 472-505 amino acids from the Central region of human MME.

Clone

965CT9-1-1

Isotype

IgG1 kappa

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MME Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

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anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reactivité: Humain WB, IHC, ELISA, StM, Coat Hôte: Souris Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB: 1:4000. IHC: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Date de péremption

6 months
Antigène

MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation

MME (MME Produits)

Synonymes

anticorps CALLA, anticorps CD10, anticorps NEP, anticorps SFE, anticorps 6030454K05Rik, anticorps C85356, anticorps Nep, anticorps neprilysin, anticorps membrane metalloendopeptidase, anticorps membrane metallo endopeptidase, anticorps membrane metallo-endopeptidase, anticorps MME, anticorps Mme

Classe de substances

Chemical

Sujet

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675, PubMed:< a href="http://www.uniprot.org/citations/8168535" target="_blank">8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:< a href="http://www.uniprot.org/citations/17101991" target="_blank">17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:< a href="http://www.uniprot.org/citations/2531377" target="_blank">2531377, PubMed:< a href="http://www.uniprot.org/citations/2972276" target="_blank">2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:< a href="http://www.uniprot.org/citations/20876573" target="_blank">20876573).

Poids moléculaire

85514

UniProt

P08473

Pathways

Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration