CYR61 anticorps (AA 143-174)

N° du produit ABIN6243134

Détail du produit anti-CYR61 anticorps

Antigène: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Épitope: AA 143-174

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYR61 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CYR61 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 143-174 amino acids from the Central region of human CYR61.

Clone: RB53929

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur CYR61

Antigène: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Autre désignation: CYR61 (CYR61 Produits)

Synonymes: anticorps CCN1, anticorps GIG1, anticorps IGFBP10, anticorps ccn1, anticorps gig1, anticorps Xcyr61, anticorps igfbp10, anticorps MGC69281, anticorps MGC69539, anticorps cyr61-l2, anticorps zgc:158158, anticorps CYR61, anticorps AI325051, anticorps Igfbp10, anticorps cysteine rich angiogenic inducer 61, anticorps cysteine-rich, angiogenic inducer, 61, anticorps cysteine-rich, angiogenic inducer, 61 like 2, anticorps cysteine rich protein 61, anticorps cysteine rich angiogenic inducer 61 S homeolog, anticorps CYR61, anticorps Cyr61, anticorps cyr61, anticorps cyr61l2, anticorps cyr61.S

Sujet: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Poids moléculaire: 42027

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding