MAPT anticorps (C-Term)

N° du produit ABIN6243259

Détail du produit anti-MAPT anticorps

Antigène: MAPT (Microtubule-Associated Protein tau (MAPT))

Épitope: AA 694-728, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPT est non-conjugé

Application: Western Blotting (WB)

Homologie: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MAPT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 694-728 amino acids from the C-terminal region of human MAPT.

Clone: RB51224

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur MAPT

Antigène: MAPT (Microtubule-Associated Protein tau (MAPT))

Autre désignation: MAPT (MAPT Produits)

Synonymes: anticorps DDPAC, anticorps FTDP-17, anticorps MAPTL, anticorps MSTD, anticorps MTBT1, anticorps MTBT2, anticorps PPND, anticorps TAU, anticorps AI413597, anticorps AW045860, anticorps Mtapt, anticorps Tau, anticorps RNPTAU, anticorps pTau, anticorps tau, anticorps xtp, anticorps MAPT, anticorps PHF-tau, anticorps slc6a6, anticorps taut, anticorps wu:fc26e12, anticorps microtubule associated protein tau, anticorps microtubule-associated protein tau, anticorps microtubule associated protein tau S homeolog, anticorps Microtubule-associated protein tau, anticorps solute carrier family 6 (neurotransmitter transporter), member 6b, anticorps MAPT, anticorps Mapt, anticorps mapt.S, anticorps LOC5580230, anticorps CpipJ_CPIJ013260, anticorps tau, anticorps slc6a6b

Sujet: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Poids moléculaire: 78928

UniProt: P10636

Pathways: Signalisation MAPK, Dynamique des Microtubules, M Phase, Regulation of Cell Size