SOX2 anticorps (C-Term)

N° du produit ABIN6243284

Cet anticorps Lapin Polyclonal détecte spécifiquement SOX2 dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SOX2 anticorps (C-Term) (ABIN6243284)

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB51412

Détail du produit anti-SOX2 anticorps

Épitope: AA 282-316, C-Term

Homologie: C, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SOX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2

Sujet: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Poids moléculaire: 34310

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis