BMI1 anticorps (C-Term)

N° du produit ABIN6243359

Cet anticorps Lapin Polyclonal détecte spécifiquement BMI1 dans WB et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour BMI1 anticorps (C-Term) (ABIN6243359)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: RB51571

Détail du produit anti-BMI1 anticorps

Épitope: AA 281-314, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BMI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 281-314 amino acids from the C-terminal region of human BMI1.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:25. WB: 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: BMI1

Sujet: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Poids moléculaire: 36949

UniProt: P35226

Pathways: Cycle Cellulaire, Autophagy