KAT5 anticorps (AA 367-398)

N° du produit ABIN6243420

L’anticorps Lapin Polyclonal anti-KAT5 a été validé pour WB. Il convient pour détecter KAT5 dans des échantillons de Humain.

Aperçu rapide pour KAT5 anticorps (AA 367-398) (ABIN6243420)

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT5 est non-conjugé

Application: Western Blotting (WB)

Clone: RB53893

Détail du produit anti-KAT5 anticorps

Épitope: AA 367-398

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KAT5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 367-398 amino acids from human KAT5.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur KAT5

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Autre désignation: KAT5

Sujet: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2.

Poids moléculaire: 58582

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway