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METTL14 anticorps (AA 2-36)

L’anticorps Lapin Polyclonal anti-METTL14 a été validé pour WB, IF et IHC (p). Il convient pour détecter METTL14 dans des échantillons de Humain et Souris.
N° du produit ABIN6243447

Aperçu rapide pour METTL14 anticorps (AA 2-36) (ABIN6243447)

Antigène

Voir toutes METTL14 Anticorps
METTL14 (Methyltransferase Like 14 (METTL14))

Reactivité

  • 30
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 29
  • 1
Lapin

Clonalité

  • 30
Polyclonal

Conjugué

  • 12
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp METTL14 est non-conjugé

Application

  • 23
  • 13
  • 13
  • 11
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB55130
  • Épitope

    • 15
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-36

    Homologie

    B

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This METTL14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the human region of human METTL14.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:2000. IHC-P: 1:250

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Date de péremption

    6 months
  • Antigène

    METTL14 (Methyltransferase Like 14 (METTL14))

    Autre désignation

    METTL14

    Sujet

    N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs.

    Poids moléculaire

    52150

    UniProt

    Q9HCE5
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