ATG16L1 anticorps

N° du produit ABIN6243484

Cité dans 1 publication. Cet anticorps anti-ATG16L1 Monoclonal Souris (Clone 54CT27-2-6) (ABIN6243484) détecte spécifiquement ATG16L1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ATG16L1 anticorps (ABIN6243484)

Antigène: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATG16L1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 54CT27-2-6

Détail du produit anti-ATG16L1 anticorps

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: Purified His-tagged ATG16L1 protein(Fragment) was used to produced this monoclonal antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:60. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ATG16L1 (ABIN6243484)

Martinez-Outschoorn, Trimmer, Lin, Whitaker-Menezes, Chiavarina, Zhou, Wang, Pavlides, Martinez-Cantarin, Capozza, Witkiewicz, Flomenberg, Howell, Pestell, Caro, Lisanti, Sotgia: "Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment." dans: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 17, pp. 3515-33, (2010) (PubMed).

Détails sur ATG16L1

Antigène: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Autre désignation: ATG16L1

Sujet: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 68265

NCBI Accession: NP_001177195, NP_001177196, NP_060444, NP_110430, NP_942593

UniProt: Q676U5

Pathways: Autophagy