Transferrin Receptor anticorps (AA 649-677)

N° du produit ABIN6243624

L’anticorps anti-Transferrin Receptor Monoclonal Souris est utilisé pour la détection de Transferrin Receptor dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Transferrin Receptor anticorps (AA 649-677) (ABIN6243624)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Western Blotting (WB)

Clone: 514CT23-4-1

Détail du produit anti-Transferrin Receptor anticorps

Épitope: AA 649-677

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogène: This TFRC antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 649-677 amino acids from human TFRC.

Isotype: IgM

Information d'application

Indications d'application: WB: 1:1000. WB: 1:100~250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: TFRC

Sujet: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Poids moléculaire: 84871

NCBI Accession: NP_001121620, NP_003225

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis