IFT57 anticorps (AA 159-193)

N° du produit ABIN6243690

L’anticorps anti-IFT57 Polyclonal Lapin est utilisé pour la détection de IFT57 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour IFT57 anticorps (AA 159-193) (ABIN6243690)

Antigène: IFT57 (Intraflagellar Transport 57 Homolog (IFT57))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFT57 est non-conjugé

Application: Western Blotting (WB)

Clone: RB57869

Détail du produit anti-IFT57 anticorps

Épitope: AA 159-193

Homologie: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IFT57 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 159-193 amino acids from the Central region of human IFT57.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur IFT57

Antigène: IFT57 (Intraflagellar Transport 57 Homolog (IFT57))

Autre désignation: IFT57

Sujet: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.

Poids moléculaire: 49108

UniProt: Q9NWB7

Pathways: Signalisation Hedgehog, Positive Regulation of Endopeptidase Activity