HSP70 1A anticorps

N° du produit ABIN6243695

Cet anticorps Lapin Polyclonal détecte spécifiquement HSP70 1A dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour HSP70 1A anticorps (ABIN6243695)

Antigène: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSP70 1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB58828

Détail du produit anti-HSP70 1A anticorps

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HSPA1A/HSPA1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human HSPA1A/HSPA1B.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur HSP70 1A

Antigène: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Autre désignation: HSPA1A/HSPA1B

Sujet: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.

UniProt: P0DMV8, P0DMV9

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process