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LRPPRC anticorps (AA 847-876)

Cet anticorps Lapin Polyclonal détecte spécifiquement LRPPRC dans WB. Il présente une réactivité envers Humain et Souris.
N° du produit ABIN6243782

Aperçu rapide pour LRPPRC anticorps (AA 847-876) (ABIN6243782)

Antigène

Voir toutes LRPPRC Anticorps
LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Reactivité

  • 40
  • 29
  • 21
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 40
Lapin

Clonalité

  • 40
Polyclonal

Conjugué

  • 16
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp LRPPRC est non-conjugé

Application

  • 29
  • 13
  • 9
  • 9
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)

Clone

RB53981
  • Épitope

    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 847-876

    Homologie

    Rat

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human LRPPRC.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Date de péremption

    6 months
  • Antigène

    LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

    Autre désignation

    LRPPRC

    Sujet

    May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

    Poids moléculaire

    157905

    UniProt

    P42704
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