LRPPRC anticorps (AA 901-1036)

N° du produit ABIN7158045

Détail du produit anti-LRPPRC anticorps

Antigène: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Épitope: AA 901-1036

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRPPRC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Leucine-rich PPR motif-containing protein, mitochondrial protein (901-1036AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LRPPRC

Antigène: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Autre désignation: LRPPRC (LRPPRC Produits)

Synonymes: anticorps CLONE-23970, anticorps GP130, anticorps LRP130, anticorps LSFC, anticorps Lrp157, anticorps 3110001K13Rik, anticorps C76645, anticorps Gp130, anticorps Lrp130, anticorps Lsfc, anticorps leucine rich pentatricopeptide repeat containing, anticorps leucine-rich pentatricopeptide repeat containing, anticorps leucine-rich PPR-motif containing, anticorps LRPPRC, anticorps Lrpprc

Sujet:

Background: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

Aliases: 130 kDa leucine-rich protein antibody, gp130 antibody, Leucine-rich PPR motif-containing protein antibody, Leucine-rich PPR-motif containing protein antibody, LPPRC_HUMAN antibody, LRP 130 antibody, lrpprc antibody, mitochondrial antibody

UniProt: P42704