LRPPRC anticorps (AA 847-876)

N° du produit ABIN6243782

Détail du produit anti-LRPPRC anticorps

Antigène: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Épitope: AA 847-876

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRPPRC est non-conjugé

Application: Western Blotting (WB)

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human LRPPRC.

Clone: RB53981

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur LRPPRC

Antigène: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Autre désignation: LRPPRC (LRPPRC Produits)

Synonymes: anticorps CLONE-23970, anticorps GP130, anticorps LRP130, anticorps LSFC, anticorps Lrp157, anticorps 3110001K13Rik, anticorps C76645, anticorps Gp130, anticorps Lrp130, anticorps Lsfc, anticorps leucine rich pentatricopeptide repeat containing, anticorps leucine-rich pentatricopeptide repeat containing, anticorps leucine-rich PPR-motif containing, anticorps LRPPRC, anticorps Lrpprc

Sujet: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

Poids moléculaire: 157905

UniProt: P42704