NDN anticorps (N-Term)

N° du produit ABIN6243906

Détail du produit anti-NDN anticorps

Antigène: NDN (Necdin Homolog (Mouse) (NDN))

Épitope: AA 75-109, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDN est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NDN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-109 amino acids from the N-terminal region of human NDN.

Clone: RB51025

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur NDN

Antigène: NDN (Necdin Homolog (Mouse) (NDN))

Autre désignation: NDN (NDN Produits)

Synonymes: anticorps LOC574323, anticorps AI528698, anticorps Peg6, anticorps NDN, anticorps HsT16328, anticorps PWCR, anticorps necdin, MAGE family member, anticorps necdin, anticorps NDN, anticorps Ndn

Sujet: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).

Poids moléculaire: 36086

UniProt: Q99608

Pathways: Neurotrophin Signaling Pathway